Our MOTS-c is a synthetic, high-purity peptide sequence identical to the endogenous human form (amino acid sequence: MRWQEMGYIFYPRKLR). It is produced under stringent laboratory conditions to ensure exceptional purity and biological activity for research purposes. As a novel mitochondrial signal, MOTS-c is a cutting-edge tool in biochemistry and molecular biology research, primarily used to investigate metabolic regulation, insulin sensitivity, exercise mimetics, and the molecular mechanisms of aging. Its high specificity makes it invaluable for advancing studies in metabolic health and longevity science.
Product Description
Our MOTS-c is a synthetic, high-purity peptide sequence identical to the endogenous human form (amino acid sequence: MRWQEMGYIFYPRKLR). It is produced under stringent laboratory conditions to ensure exceptional purity and biological activity for research purposes. As a novel mitochondrial signal, MOTS-c is a cutting-edge tool in biochemistry and molecular biology research, primarily used to investigate metabolic regulation, insulin sensitivity, exercise mimetics, and the molecular mechanisms of aging. Its high specificity makes it invaluable for advancing studies in metabolic health and longevity science.
Attributes
| English Name | MOTS-c (Mitochondrial Derived Peptide) | Density | / |
| CAS NO | 1627580-42-9 | Index of Refraction | / |
| Molecular Formula | C₉₆H₁₄₇N₃₁O₂₆ | Storage Condition | 20°C or below, desiccated |
| Mol. wt. | 2176.4 g/mol | Solubility | Soluble in water, PBS buffer |
| EINECS No. | / | Form | Lyophilized Powder |
| MDL No. | MFCD32614451 | Colour | White to off-white powder |
| Melting Points | / | PH Value | / |
| Stability | Stable when stored lyophilized at -20°C or below. Avoid repeated freeze-thaw cycles. Reconstituted solutions should be aliquoted and stored at -20°C or -80°C for short-term use. | ||
Nutritional Composition
As a highly purified synthetic peptide, its composition is defined solely by its specific amino acid sequence. It contains no fats, carbohydrates, or other macro-nutrients. This product is for research use only.
MOTS-c has been shown to enhance glucose uptake in cells and improve insulin sensitivity, particularly in muscle tissue. It helps restore metabolic homeostasis and may counteract diet-induced obesity and insulin resistance in preclinical models.
It activates protective cellular pathways, including the AICAR/AMPK pathway, enhancing the body's resilience to metabolic stress and potentially mimicking some beneficial effects of exercise and caloric restriction.
Research suggests MOTS-c helps maintain muscle strength and integrity during aging. It is believed to protect against age-related skeletal muscle decline and support overall physical performance by optimizing mitochondrial function and reducing oxidative stress.
A fundamental tool for in vitro and in vivo studies investigating the role of mitochondrial-nuclear communication in metabolism, obesity, type 2 diabetes, and the biology of aging.
Used in preclinical research to study potential "exercise mimetic" effects, examining how MOTS-c influences energy expenditure, fat utilization, and physical endurance without physical activity.
Due to its promising metabolic and anti-aging properties, it is a compound of high interest in the early-stage research and development of next-generation supplements for metabolic health and active-ingredient skincare formulations aimed at promoting cellular vitality and resilience. (Note: These applications are primarily at the research stage.)

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