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Product Description
Azelaic acid typically appears as a white to off - white crystalline powder. It has a melting point of around 106 - 108 °C. While it is sparingly soluble in water, it shows better solubility in organic solvents such as ethanol and propylene glycol. This solubility profile is important for its incorporation into different skincare formulations. Its molecular structure, with two carboxylic acid groups, enables it to interact with various biological pathways in the skin, contributing to its multifunctional properties. However, its relatively low solubility in water can pose challenges in formulating water - based products, leading to the use of techniques like micronization or encapsulation to improve its dispersion.
Attributes
| English Name | Azelaic Acid |
| CAS NO | 123 - 99 - 9 |
| Molecular Formula | C₉H₁₆O₄ |
| Molecular Weight | 188.22 g/mol |
| Appearance | White to off - white crystalline powder |
| Melting Point | 106 - 108 °C |
| Density | Approximately 1.225 g/cm³ |
| Solubility | Sparingly soluble in water; soluble in ethanol, propylene glycol |
| Stability | Stable under normal storage conditions; may decompose under extreme heat or in the presence of strong acids/bases |
Antibacterial Activity
Azelaic acid exhibits potent antibacterial properties, particularly against Cutibacterium acnes (formerly known as Propionibacterium acnes), a key bacterium associated with acne. It works by inhibiting bacterial protein synthesis, thereby reducing the population of these bacteria in the hair follicles. This action helps to clear up existing acne lesions and prevent new ones from forming. Research has shown that continuous topical application of azelaic acid for 2 - 3 months can significantly decrease the number of skin bacteria and follicular C. acnes, without the development of bacterial resistance, which is a common concern with antibiotic - based treatments.
Anti - inflammatory Effects
It is a powerful anti - inflammatory agent. Azelaic acid scavenges free radicals and inhibits mitochondrial oxidoreductases, reducing the generation of pro - inflammatory oxygen derivatives in neutrophils. This leads to a decrease in inflammation, which is beneficial for treating conditions like acne, rosacea, and other inflammatory skin disorders. By reducing redness, swelling, and irritation, it helps to calm the skin and promote a more even complexion. In the case of acne, its anti - inflammatory action can also reduce the appearance of post - inflammatory hyperpigmentation, a common issue for those with acne - prone skin.
Keratolytic and Comedolytic Properties
Azelaic acid acts as a keratolytic and comedolytic agent. It regulates the abnormal growth of skin cells lining the hair follicles by inhibiting the proliferation and differentiation of human keratinocytes. This helps to prevent the formation of comedones (blackheads and whiteheads) by normalizing the keratinization process. By exfoliating the skin gently, it unclogs pores, allowing for better skin respiration and reducing the likelihood of pore - blockage - related skin problems. This property makes it suitable for treating both comedonal and inflammatory acne.
Pigmentation Reduction
As a tyrosine inhibitor, azelaic acid is effective in reducing skin pigmentation. It targets the abnormal activity of melanocytes, the cells responsible for producing melanin, the pigment that gives color to the skin. By inhibiting the enzyme tyrosinase, which is crucial in the melanin synthesis pathway, azelaic acid helps to lighten hyperpigmented areas such as age spots, sunspots, and melasma. Notably, it has a greater effect on abnormal melanocytes compared to normal ones, making it a preferred choice for treating pigmentation disorders while minimizing the risk of over - lightening normal skin.
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Skincare Products
• Acne Treatments: It's a key ingredient in anti - acne creams, gels, and serums. For example, the 15 - 20% azelaic acid gel is often prescribed for mild to moderate acne. Brands like Paula's Choice offer azelaic acid - based products that target acne - causing bacteria, unclog pores, and reduce inflammation.
• Hyperpigmentation Correctors: In serums and creams formulated for pigmentation issues, azelaic acid helps fade dark spots. Some products combine it with other brightening agents like vitamin C or niacinamide for enhanced results.
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Dermatological Treatments
• Rosacea Management: Doctors may recommend 15% azelaic acid gel for treating papulopustular rosacea, as it reduces the bumps and redness associated with the condition.
• Periocular and Periorificial Dermatitis: Although not as widely known, azelaic acid can be used to treat these less common skin conditions, helping to soothe inflammation and improve skin appearance.
Research and Innovation
Our commitment to excellence extends beyond production. We invest in ongoing research and development to stay at the forefront of ergothioneine science. This ensures that our products are based on the latest findings and are continuously improved for maximum effectiveness.
Sustainability and Ethics
At Shaanxi Bieyouth Biotech Co.,Ltd. we are committed to sustainable and ethical practices. We source our raw materials responsibly and ensure that our production processes have a minimal environmental impact. Our dedication to ethical standards is reflected in every aspect of our business, from our supply chain to our customer relationships.
Customer Trust
We understand that trust is earned. That's why we prioritize transparency and communication with our customers. We provide detailed information about our products, their benefits, and the science behind them. Our goal is to empower our customers to make informed decisions about their health and well-being.
Global Reach
Ergothioneine's benefits are universal, and so is our reach. We distribute our products worldwide, making this elite antioxidant accessible to health-conscious individuals across the globe. Our international presence allows us to serve a diverse range of customers and contribute to global health.
The Future of Health
As we continue to explore the potential of ergothioneine, we are excited about the future of health and wellness. We believe that by offering high-quality ergothioneine supplements, we are contributing to a healthier, more vibrant world. Join us in this journey towards optimal health and discover the difference ergothioneine can make in your life.
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About Us
Shaanxi Bieyouth Biotech Co., Ltd. is proud to offer Azelaic Acid, a cutting-edge supplement for those seeking to enhance their cellular health and protect against the ravages of time. By incorporating our Azelaic Acid into your health regimen, you are taking a proactive step towards safeguarding your body's cells and promoting a longer, healthier life. Experience the power of this elite antioxidant and embrace the benefits of Azelaic Acid for your well-being.
