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Product Description
Melittin has a higher concentration of active ingredients (specifically the main hemolytic and antimicrobial peptide) and is more efficiently absorbed compared to raw bee venom or unprocessed apitoxin. It is commonly used as an ingredient in pharmaceuticals, health supplements, and topical skincare products.
Attributes
| English Name | Melittin | Density | / |
| CAS NO | 20449-79-0 | Index of Refraction | / |
| Molecular Formula | C131H229N39O31 | Storage Condition | Cool Dry Area |
| Mol. wt. | 2846.47 | Solubility | / |
| EINECS No. | 629-303-1 | Form | powder |
| MDL No. | / | Colour | Brown Yellow |
| Melting Points | / | PH Value | / |
| Stability | Melittin has good stability under normal temperature, dry, light-proof and sealed conditions, and is suitable for long-term storage. | ||
Nutritional Composition
The sole main component of Melittin is the purified peptide itself. This standardized product is derived directly from the concentrated and lyophilized active principles of honeybee venom, ensuring a pure and unadulterated substance.
Exerts Potent Anti-inflammatory Effects
Melittin, the major peptide component of honeybee venom, acts as a powerful anti-inflammatory agent by inhibiting the NF-κB pathway and suppressing the production of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6. It helps reduce inflammation in conditions like arthritis, dermatitis, and other inflammatory disorders. This peptide is widely studied in pharmaceutical research for individuals with chronic inflammatory conditions, autoimmune diseases, or acute inflammatory responses.
Provides Broad-Spectrum Antimicrobial Activity
Melittin exhibits strong antimicrobial properties against a wide range of pathogens, including Gram-positive and Gram-negative bacteria, fungi, and viruses. By disrupting microbial cell membranes, it effectively kills bacteria such as Staphylococcus aureus, Escherichia coli, and Candida albicans. It is a promising natural ingredient in topical antimicrobial formulations and infection control products, particularly valuable for wound care and skin infections.
Supports Wound Healing and Tissue Regeneration
Melittin promotes wound healing by enhancing keratinocyte migration, stimulating angiogenesis, and modulating the inflammatory phase of wound repair. Its ability to reduce bacterial load and control excessive inflammation contributes to faster and cleaner healing of cuts, burns, and ulcers. It is increasingly explored in regenerative medicine and topical wound care products.
Exhibits Anti-tumor and Anti-cancer Properties
Research has shown that melittin can induce apoptosis (programmed cell death) in various cancer cell lines, including breast, liver, lung, and prostate cancer cells. It acts by disrupting cell membranes and activating caspase-dependent pathways, making it a potential natural adjuvant in oncology therapeutics. While still in experimental stages, melittin-based formulations are being developed for targeted cancer therapy.
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Application in Pharmaceuticals and Topical Therapeutics
Melittin is a sought-after active peptide in the pharmaceutical and topical therapeutic categories. It is commonly formulated into standalone ointments, gels, or injectable solutions for its potent anti-inflammatory and antimicrobial effects, as well as in complex formulations combined with other bioactive agents such as hyaluronic acid, silver nanoparticles, or corticosteroids. Beyond conventional dosage forms, it is increasingly incorporated into advanced wound dressings, antimicrobial coatings, and targeted cancer therapy systems, targeting healthcare professionals and researchers seeking natural-origin peptide solutions for inflammation control, infection management, and oncological applications.
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Application in Skincare and Dermatological Products
Due to its strong anti-inflammatory, antimicrobial, and tissue-regenerating properties, Melittin is gaining attention in the dermo-cosmetic industry. Its ability to modulate inflammatory responses helps calm irritated skin conditions such as acne, eczema, or psoriasis, while its antimicrobial activity reduces pathogenic load on the skin surface. By promoting wound healing and stimulating collagen synthesis, it is an effective ingredient in post-procedure repair creams, acne spot treatments, and anti-aging formulations (at very low, non-irritating concentrations). It is particularly valued in products designed for inflammatory skin conditions, as it aids in reducing redness, preventing infection, and supporting skin barrier restoration.
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Application in Pain Management and Anti-arthritic Formulations
Melittin is increasingly utilized in the growing pain management and natural anti-arthritic category. Its ability to inhibit NF-κB and reduce pro-inflammatory cytokines such as TNF-α and IL-1β contributes to significant relief from joint pain and swelling associated with rheumatoid arthritis and osteoarthritis. It is commonly incorporated into topical analgesic gels, transdermal patches, and apitherapy formulations, often combined with complementary ingredients such as glucosamine, chondroitin, or capsaicin. This peptide appeals to patients and clinicians seeking natural, peptide-based alternatives for managing chronic inflammatory pain and improving joint mobility.
Research and Innovation
Our commitment to excellence extends beyond production. We invest in ongoing research and development to stay at the forefront of Melittin science. This ensures that our products are based on the latest findings and are continuously improved for maximum effectiveness.
Sustainability and Ethics
At Shaanxi Bieyouth Biotech Co.,Ltd. we are committed to sustainable and ethical practices. We source our raw materials responsibly and ensure that our production processes have a minimal environmental impact. Our dedication to ethical standards is reflected in every aspect of our business, from our supply chain to our customer relationships.
Customer Trust
We understand that trust is earned. That's why we prioritize transparency and communication with our customers. We provide detailed information about our products, their benefits, and the science behind them. Our goal is to empower our customers to make informed decisions about their health and well-being.
Global Reach
Melittin's benefits are universal, and so is our reach. We distribute our products worldwide, making this elite antioxidant accessible to health-conscious individuals across the globe. Our international presence allows us to serve a diverse range of customers and contribute to global health.
The Future of Health
As we continue to explore the potential of Melittin, we are excited about the future of health and wellness. We believe that by offering high-quality Melittin supplements, we are contributing to a healthier, more vibrant world. Join us in this journey towards optimal health and discover the difference Melittin can make in your life.
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About Us
Shaanxi Bieyouth Biotech Co., Ltd. is proud to offer Melittin, a cutting-edge supplement for those seeking to enhance their cellular health and protect against the ravages of time. By incorporating our Melittin into your health regimen, you are taking a proactive step towards safeguarding your body's cells and promoting a longer, healthier life. Experience the power of this elite antioxidant and embrace the benefits of Melittin for your well-being.






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