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Ferrous Bisglycinate: The Highly Bioavailable Chelated Iron for Gentle, Effective Anemia Support and Iron Fortification
Nutritional Supplement

Ferrous Bisglycinate: The Highly Bioavailable Chelated Iron for Gentle, Effective Anemia Support and Iron Fortification

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Ferrous Bisglycinate, also known as iron bisglycinate chelate or ferrous glycinate, is a third-generation iron supplement formed by chelating a ferrous iron ion (Fe²⁺) with two glycine molecules. This unique five-membered ring chelate structure shields the iron from interacting with other food components, significantly enhancing its bioavailability while minimizing the gastrointestinal irritation commonly associated with conventional iron salts such as ferrous sulfate. As a highly stable, water-soluble, and odorless iron source, it is widely used in dietary supplements, functional foods, and clinical nutrition for the prevention and treatment of iron deficiency anemia.

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    Product Description

    Our Ferrous Bisglycinate is a high-purity, food-grade and pharmaceutical-grade chelated iron produced through controlled synthesis from ferrous iron and glycine, followed by spray drying to yield a fine, free-flowing powder. The product appears as a dark brown or grayish-green crystalline powder with a slight metallic, sweetish taste and excellent water solubility. The chelation is confirmed through analytical characterization, ensuring true chelate formation rather than a simple physical mixture. With an assay of ≥99% and elemental iron content of 19.0–23.8%, it complies with relevant pharmacopeial standards and is manufactured under strict cGMP conditions to ensure consistent particle size distribution and reliable flow characteristics. Its high stability across a broad pH range (remains completely soluble at pH 6, unlike ferrous sulfate which precipitates) allows for flexible incorporation into diverse food and beverage matrices. It is ideal for formulating iron supplements (capsules, tablets, granules, oral liquids), fortified foods and beverages, and clinical nutrition products.
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    Attributes

    English Name Ferrous Bisglycinate Density 1.898 g/cm³ (at 20°C)
    CAS NO 20150-34-9 Index of Refraction /
    Molecular Formula C₄H₈FeN₂O₄ Storage Condition Cool Dry Area (sealed, protected from light and moisture)
    Mol. wt. 203.96 g/mol Solubility Soluble in water and aqueous acid
    EINECS No. 606-444-7 Form powder
    MDL No. / Colour Dark brown or grayish-green
    Melting Points >162°C (dec.) PH Value ~8 (1% solution)
    Stability Good stability under normal temperature, dry, light-proof and sealed conditions. The chelate structure maintains solubility across a broad pH range (completely soluble at pH 6).
    Application Scenarios of Tremella Exosomes
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    Nutritional Composition

    Ferrous Bisglycinate is a high‑quality chelated nutritional iron ingredient. Formed by ferrous ions chelating with glycine, its stable five‑membered‑ring structure delivers superior bioavailability versus common inorganic iron salts. It greatly lowers gastrointestinal irritation risks. With favorable water‑solubility and pH stability, this nutrient is widely used in capsules, tablets and fortified functional foods for effective iron supplementation and prevention of iron‑deficiency anemia. It complies with global food‑grade raw material standards.

    Health Benefits

    Ferrous Bisglycinate's health benefits are multifaceted, making it a valuable addition to any health regimen:

    Cognitive-Wellness
    Provides Superior Bioavailability with High Absorption Rate
    The chelated structure protects the ferrous iron from dietary inhibitors (such as phytates and polyphenols) and allows it to be absorbed intact through the intestinal mucosa via active transport mechanisms. The absorption rate of ferrous bisglycinate is approximately 3–5 times that of ferrous sulfate, with some studies reporting absorption rates up to 95%.
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    Gentle on the Gastrointestinal Tract with Minimal Side Effects
    Unlike conventional iron salts, ferrous bisglycinate does not release free Fe²⁺ ions in the stomach, thereby avoiding the oxidative stress and mucosal irritation responsible for nausea, constipation, and abdominal discomfort. Clinical trials confirm significantly better tolerability compared to ferrous sulfate, with reduced gut inflammation markers.
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    Effective for Iron Deficiency Anemia Prevention and Treatment
    Clinical studies demonstrate that daily supplementation with 30 mg of iron bisglycinate significantly increases serum ferritin levels (from 24.1 to 32.3 ng/mL by day 15) and effectively improves hemoglobin, red blood cell count, and hematocrit in patients with iron deficiency anemia. It is particularly valuable for pregnant women, children, and individuals who cannot tolerate conventional iron supplements.
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    Improves Cognitive Function and Physical Performance
    By correcting iron deficiency, ferrous bisglycinate supports optimal oxygen transport and energy metabolism, which may improve concentration, memory, and cognitive performance. Research also suggests it can help enhance exercise capacity and reduce fatigue in athletes with iron deficiency, even without frank anemia.

    Applications

    Ferrous Bisglycinate is suitable for a variety of health-conscious individuals:
    Nutraceuticals
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    Dietary Supplements
    Formulated into capsules, tablets, granules, and oral liquids for the prevention and treatment of iron deficiency anemia. It is particularly suitable for sensitive populations including pregnant women, children, and the elderly who are prone to gastrointestinal side effects from traditional iron supplements.
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    Functional Foods and Beverages
    Used as a nutritional fortifier in dairy products (modified milk powder, fortified milk), beverages (juice, plant protein drinks, solid beverages), baked goods (bread, biscuits, cereal products), meat products, infant formula, soy powder, jelly, and confectionery. Recommended addition levels: 60–200 mg/kg in modified milk powder; 14–26 mg/kg in rice and wheat flour products.
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    Clinical Nutrition and Medical Foods
    Applied in enteral nutrition formulas and nutritional support products for patients with iron deficiency anemia, including those undergoing cancer treatment, post-surgical recovery, or with chronic inflammatory conditions.

    Additional Information

    Research and Innovation
    Our commitment to excellence extends beyond production. We invest in ongoing research and development to stay at the forefront of Ferrous Bisglycinate science. This ensures that our products are based on the latest findings and are continuously improved for maximum effectiveness.
    Sustainability and Ethics
    At Shaanxi Bieyouth Biotech Co.,Ltd. we are committed to sustainable and ethical practices. We source our raw materials responsibly and ensure that our production processes have a minimal environmental impact. Our dedication to ethical standards is reflected in every aspect of our business, from our supply chain to our customer relationships.
    Customer Trust
    We understand that trust is earned. That's why we prioritize transparency and communication with our customers. We provide detailed information about our products, their benefits, and the science behind them. Our goal is to empower our customers to make informed decisions about their health and well-being.
    Global Reach
    Ferrous Bisglycinate's benefits are universal, and so is our reach. We distribute our products worldwide, making this elite antioxidant accessible to health-conscious individuals across the globe. Our international presence allows us to serve a diverse range of customers and contribute to global health.
    The Future of Health
    As we continue to explore the potential of Ferrous Bisglycinate, we are excited about the future of health and wellness. We believe that by offering high-quality Ferrous Bisglycinate supplements, we are contributing to a healthier, more vibrant world. Join us in this journey towards optimal health and discover the difference Ferrous Bisglycinate can make in your life.

    Quality Assurance

    We uphold strict quality control standards to ensure that our Ferrous Bisglycinate meet the highest standards of purity and efficacy. Each batch is rigorously tested to confirm the presence of the active compound and to screen for potential contaminants.

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    About Us

    Shaanxi Bieyouth Biotech Co., Ltd. is proud to offer Ferrous Bisglycinate, a cutting-edge supplement for those seeking to enhance their cellular health and protect against the ravages of time. By incorporating our Ferrous Bisglycinate into your health regimen, you are taking a proactive step towards safeguarding your body's cells and promoting a longer, healthier life. Experience the power of this elite antioxidant and embrace the benefits of Ferrous Bisglycinate for your well-being.
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